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Symbol
Name
ID
Plau
plasminogen activator, urokinase
MGI:97611
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Epistaxis
Joint hemorrhage
Menorrhagia
Bruising susceptibility
Impaired epinephrine-induced platelet aggregation
Thrombocytopenia
Disease(s) Associated with PLAU
Quebec platelet disorder

Mouse Phenotypes
hematopoietic system phenotype
impaired macrophage chemotaxis
decreased T cell proliferation
impaired neutrophil phagocytosis
increased neutrophil cell number
increased lymphocyte cell number
increased monocyte cell number
abnormal neutrophil physiology
impaired granulocyte bactericidal activity
abnormal macrophage physiology
Availability Mouse Genotype
Plautm1b(EUCOMM)Wtsi/Plautm1b(EUCOMM)Wtsi
Plautm1Mlg/Plautm1Mlg *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory